Experience of using tacrolimus as a part of a complex therapy of atopic dermatitis

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Abstract

This review presents the results of international and Russian clinical studies conducted to assess the efficacy and safety of topical calcineurin inhibitors (TCIs) for the treatment of atopic dermatitis. The main mechanisms of action of TCIs are described. The authors demonstrate the advantages of Tacrolimus belonging to the TCI group. Due to the hydrophilic drug form and pharmacoeconomic index promoting compliance with treatment, it is possible to consider the new drug Tacropic (0.1% and 0.03% Tacrolimus ointments) as the optimum topical drug for the treatment of moderate to severe and severe forms of atopic dermatitis in adults and children.

About the authors

N. N. Filimonkova

FGBU “Ural Research Institute of Dermatology and Venereology and immunopathology” Russian Ministry of Health

Author for correspondence.
Email: noemail@neicon.ru
Russian Federation

Y. V. Kascheeva

FGBU “Ural Research Institute of Dermatology and Venereology and immunopathology” Russian Ministry of Health

Email: noemail@neicon.ru
Russian Federation

M. S. Kolbina

Moscow Health Department clinic № 46

Email: kolbinamary@mail.ru
Russian Federation

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Copyright (c) 2016 Filimonkova N.N., Kascheeva Y.V., Kolbina M.S.

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