Vestnik dermatologii i venerologiiVestnik dermatologii i venerologii0042-46092313-6294Rossijskoe Obschestvo Dermatovenerologov i Kosmetologov48810.25208/0042-4609-2019-95-2-81-86Complex application of cosmetics products of the line A “Skinormil” in the care of the skin of patients with acneVintserskayaG. A.Galina A. Vintserskaya* — Cand. Sci. (Med.), Assoc. Prof., Assoc. Prof.bulovich31@mail.ruhttps://orcid.org/0000-0001-6758-1311NgemaM. V.Maria V. Ngema — Cand. Sci. (Med.), Assoc. Prof., Assoc. Prof.fake@neicon.ruhttps://orcid.org/0000-0002-5018-2629ProkhorovD. V.Dmitry V. Prokhorov — Dr. Sci. (Med.), Assoc. Prof., Prof.fake@neicon.ruhttps://orcid.org/0000-0003-2916-8336KuznetsovaM. Yu.Marina Yu. Kuznetsova — Research Assistantfake@neicon.ruhttps://orcid.org/0000-0001-9227-4751SherengovskayaYu. V.Yulia V. Sherengovskaya — Research Assistantfake@neicon.ruhttps://orcid.org/0000-0002-9939-2387Medical Academy named after S. I. Georgievsky, V. I. Vernadsky Crimean Federal University1704201995281861707201917072019Copyright © 2019, Vintserskaya G.A., Ngema M.V., Prokhorov D.V., Kuznetsova M.Y., Sherengovskaya Y.V.2019<p>The article outlines the questions of pathogenesis of acne as well as clinical trial data, which indicate that the skin of patients with acne needs comprehensive care with therapeutic cosmetics. Long term use of medical cosmetics has a positive effect on the course of acne disease. The basis of the study is the use of cosmetics line A “Skinormil” including the patented complex Citobiol lRIS, zinc sulfate and vitamin A. Seventy-four patients with acne of the first, second and third severity were monitored and it was recommended them a comprehensive skin care with medical cosmetics. According to the analysis of the clinical picture, it was concluded that on the background of proper care, there is a positive dynamics in the course of acne.</p>acnepathogenesiscosmeticsакнепатогенезкосметика[1. Демина О. М. Угревая болезнь. Комбинированная лазерная и фотодинамическая терапия: руководство для врачей. М.: Бином, 2017. С. 16–18. [Demina O. M. Acne disease. Combined laser and photodynamic therapy: A guide for physicians. Moscow: Binom, 2017. P. 16–18. (In Russ.)]][2. Danby F. W. Acne: Causes and Practical Management. WileyBlackwell, 2015.][3. Потекаев Н. Н., Горячкина М. В., Белоусова Т. А. Акне: современный взгляд на проблему. Consilium medicum. 2008;(1 прил.: Дерматология):16–21. [Potekaev N. N., Goryachkina M. V., Belousova T. A. Acne: A modern view on the problem. Consilium medicum. 2008;(1 Appendix: Dermatology):16–21. (In Russ.)]][4. Кубанова А. А. (ред.) Клинические рекомендации. Дерматовенерология. М.: ДЭКС-Пресс, 2007. С. 9–28. [Kubanova A. A. (ed.) Clinical guidelines. Dermatovenereology. Moscow: DEKS-Press, 2007. P. 9–28. (In Russ.)]][5. Биткина О. А., Никулин Н. К. Акне: этиология, патогенез, вопросы терапии. Современные проблемы дерматовенерологии, иммунологии и врачебной косметологии. 2009;4(7):67–70. [Bitkina O. A., Nikulin N. K. Acne: Etiology, pathogenesis, therapy issues. Modern problems of dermatovenerology, immunology and medical cosmetology. 2009;4(7):67–70. (In Russ.)]][6. Адаскевич В. П. Акне вульгарные и розовые. М.: Медицинская книга, 2005. [Adaskevich V. P. Acne vulgar and pink. Moscow: Medicinskaya kniga, 2005. (In Russ.)]][7. Do T. T., Zarkhin S., Orringer J. S. Computer-assisted alignment and tracking of acne lesions indicate that most inflammatory lesions arise from comedones and de novo. J Am Acad Dermatol. 2008;58(4):603–608.][8. Leeming J., Holland K., Cunliffe W. J. The microbial ecology of pilosebaceous units isolated from human skin. J Gen Microbiol. 1984;130(4):803–807.][9. Leeming J., Holland K., Cunliffe W. J. The pathological and ecological significance of microorganisms colonizing acne vulgaris comedones. J Med Microbiol. 1985;20:11–16.][10. Lavker R. M., Leyden J. J., McGinley K. J. The relationship between bacteria and the abnormal follicular keratinization in acne vulgaris. J Invest Dermatol. 1981;77(3):325–330.]