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Нейротрофины и нейропептиды как медиаторы воспаления при хронических дерматозах

https://doi.org/10.25208/0042-4609-2014-0-6-57-61

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Аннотация

В обзоре литературы рассматривается роль нейротрофинов и нейропептидов в развитии воспалительной реакции в коже при хронических воспалительных дерматозах. Описаны воспалительные эффекты нейротрофина фактора роста нервов, нейропептидов субстанции P и пептида, связанного с геном кальцитонина. Рассмотрено участие факторов, влияющих на состояние иннервации кожи и развитие воспаления, - нейротрофина фактора роста нервов и эпидермального фактора роста амфирегулина, фактора редукции нервов семафорина-3А. Поиск и применение антагонистов провоспалительных эффектов нейропептидов, нейротрофинов и эпидермального фактора роста могут быть новым подходом к лечению хронических воспалительных дерматозов.

Об авторах

А. А. Кубанова
ФГБУ «Государственный научный центр дерматовенерологии и косметологии» Минздрава России
Россия


В. А. Смольянникова
ГБОУ ВПО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России
Россия


В. В. Чикин
ФГБУ «Государственный научный центр дерматовенерологии и косметологии» Минздрава России
Россия


А. Э. Карамова
ФГБУ «Государственный научный центр дерматовенерологии и косметологии» Минздрава России
Россия


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Для цитирования:


Кубанова А.А., Смольянникова В.А., Чикин В.В., Карамова А.Э. Нейротрофины и нейропептиды как медиаторы воспаления при хронических дерматозах. Вестник дерматологии и венерологии. 2014;(6):57-61. https://doi.org/10.25208/0042-4609-2014-0-6-57-61

For citation:


Kubanova A.A., Smolyannikova V.A., Chikin V.V., Karamova A.E. Neurotrophins and neuropeptides as inflammatory mediators in case of chronic dermatosis. Vestnik dermatologii i venerologii. 2014;(6):57-61. (In Russ.) https://doi.org/10.25208/0042-4609-2014-0-6-57-61

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