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Новая информация о топической фотодинамической терапии в лечении рака кожи

https://doi.org/10.25208/0042-4609-2014-0-6-26-34

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Аннотация

Местная фотодинамическая терапия стала общепризнанным вариантом лечения поверхностного немеланомного рака кожи и имеет под собой существенную доказательную базу. В статье рассмотрены новые фотосенсибилизирующие средства и источники света, а также новые протоколы, которые расширяют возможности лечения не только очагов поражений, но и кожных полей. фотодинамическая терапия (ФДТ) под воздействием дневного света является альтернативой традиционной ФДТ, проводимой в кабинетах врача и больницах, а также существенно снижает болевые ощущения. Несмотря на то, что в большинстве исследований эффективность ФДТ оценивают у иммунокомпетентных пациентов, растет объем данных в пользу того, чтобы рассматривать местную ФДТ в качестве варианта, позволяющего снизить нагрузку со стороны рака кожи у пациентов после трансплантации органов. флюоресценция, связанная с применением фотосенсибилизирующих средств, может помочь в определении границ очагов до проведения полномасштабной терапии светом, а также является полезным дополнением при лечении пациентов в случаях, когда диагностическая неопределенность или нечеткие контуры очагов затрудняют проведение клинического лечения. ФДТ также обладает существенными преимуществами, задерживая и предотвращая развитие новых очагов рака, а в сочетании с общепризнанным фотоомолаживающим эффектом представляет собой новую форму эффективной терапии, которая позволяет бороться с определенными формами поверхностного рака кожи, может предотвращать появление новых очагов, а также способствует достижению фотоомолаживающего эффекта на обработанных участках кожи.

Об авторах

C. Morton
Stirling Community Hospital
Россия


R. Szeimies
Klinikum Vest GmbH
Россия


L. Braathen
Dermatology Bern
Россия


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., ., . Новая информация о топической фотодинамической терапии в лечении рака кожи. Вестник дерматологии и венерологии. 2014;(6):26-34. https://doi.org/10.25208/0042-4609-2014-0-6-26-34

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Morton C.A., Szeimies R.-., Braathen L.R. Update on topical photodynamic therapy for skin cancer. Vestnik dermatologii i venerologii. 2014;(6):26-34. (In Russ.) https://doi.org/10.25208/0042-4609-2014-0-6-26-34

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ISSN 0042-4609 (Print)
ISSN 2313-6294 (Online)