Bullous pemphigoid. Сlinic, Diagnosis and Treatment

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Abstract


The article describes modern views on the predisposing factors, features, immunological changes and link with the histocompatibility antigens HLA, the role of circulating autoantibodies, cytokines, chemokines, matrix metalloproteinases and BP180 (BPAg2) и BP230 (BPAg1), those role in the pathogenesis of the bullous pemphigoid and their correlation with the activity of pathological process in patients with bullous pemphigoid. Described experimental model of the disease in animals, modern medications and methods of treatment of this disease.

M. B. Drozhdina

Kirov State Medical University, Ministry of Health of the Russian Federation

Author for correspondence.
Email: drozhdina@yandex.ru

Russian Federation

D.Sci. (Medicine), Associate Professor, Department of Dermatovenereology and Cosmetology

S. V. Koshkin

Kirov State Medical University, Ministry of Health of the Russian Federation

Email: koshkin_sergei@mail.ru

Russian Federation

D.Sci. (Medicine), Prof., Head of the Department of Dermatovenereology and Cosmetology

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