Particular features of angiogenesis in lesions in patients suffering from basal cell epithelioma

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Abstract


Basal cell epithelioma is one of the most frequent malignant skin neoplasms. Angiogenesis plays an important part in the development of basal cell epithelioma. The article presents a review of the angiogenesis of this tumor with the help the immunohistochemistry analysis using CD31 and CD34 markers. The authors established a reliable relationship between the number of vessels expressing CD31 and those expressing CD34 in the superficial and nodular forms of the tumor as well as superficial, multi-center, nodular and infiltrative basal cell epitheliomas. A comparison of the number of vessels expressing CD31 and CD34 markers in different histological types made revealed a trend to their growth in the infiltrative type vs. superficial, multi-center and nodular ones.

A. N. Khlebnikova

ГБОУ ВПО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России

Author for correspondence.
Email: noemail@neicon.ru

Russian Federation

N. V. Novoselova

ГБОУ ВПО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России

Email: noemail@neicon.ru

Russian Federation

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