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Хроническое воспаление, инсулинорезистентность, псориаз - что общего?

https://doi.org/10.25208/0042-4609-2016-0-5-110-115

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Аннотация

Псориаз признан системным иммуновоспалительным заболеванием. Установлено, что псориаз развивается под влиянием хронического системного воспаления и индуцируемой системным воспалением инсулинорезистентности на определенной генетической основе, т. е. является одной из клинических форм иммунометаболической болезни наряду с атеросклерозом, гипертонической болезнью, сахарным диабетом 2-го типа, ожирением и многими другими заболеваниями, тесная связь которых с псориазом установлена. Знание этиологии, патогенеза и молекулярных механизмов связи с другими клиническими формами иммунометаболической патологии открывает новые пути профилактики и лечения псориаза. Учитывая, что другие ассоциированные с псориазом заболевания, протекающие скрыто, часто имеют большее прогностическое значение для жизни и здоровья больного, чем легкие или среднетяжелые формы псориаза, необходимо не ограничиваться только констатацией диагноза и симптоматическим лечением, а активно участвовать в профилактике. Дебатируется вопрос о применении средств, подавляющих системное воспаление и инсулинорезистентность, в терапии псориаза.

Об авторе

М. С. Расин
ВГУЗ «Украинская медицинская стоматологическая академия»
Россия


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Для цитирования:


Расин М.С. Хроническое воспаление, инсулинорезистентность, псориаз - что общего? Вестник дерматологии и венерологии. 2016;(5):20-24. https://doi.org/10.25208/0042-4609-2016-0-5-110-115

For citation:


Rasin M.S. Chronic inflammation, insulin resistance, psoriasis - which have in common? Vestnik dermatologii i venerologii. 2016;(5):20-24. (In Russ.) https://doi.org/10.25208/0042-4609-2016-0-5-110-115

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