Zineryt: external therapy of acne

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Abstract


Acne is a socially significant disease affecting an overwhelming majority of teenagers, which often results in serious social disadaptation. The problem of acne treatment remains urgent especially taking into consideration the fact that the respective pathogen, P. acnes, demonstrates a growth in its resistance. The problem can be solved by using a combination therapy comprising resistance inhibiting drugs along with antibiotics. The erythromycin and zinc solution is one of the most promising combinations.

T. A. Korchevaya

Clinics of acne and skin rehabilitation

Author for correspondence.
Email: tamaramed@yandex.ru

Russian Federation

  1. Shahtmeyster I.J., Kubanova A.A., Butov Ya.S., Kazei D.V. Study of the efficacy and safety of erythromycin-zinc complex in patients with acne.Vestn dermatol i venerol 1999; 1: 19-22. [Шахтмейстер И.Я., Кубанова А.А., Бутов Ю.С., Казей Д.В. Изучение эффективности и безопасности эритромицин-цинкового комплекса у больных с угревой сыпью. Вестн дерматол и венерол 1999; 1: 19-22.]
  2. Korchevaya T.A. Acne scars, new possibilities of their treatment and prevention. Les nouvelles esthetiques 2012; 6. [Корчевая Т.А. Рубцы после акне: новые возможности их лечения и профилактики. Les nouvelles esthetiques 2012; 6.] Литература
  3. European guidelines for the treatment of acne, based on the principles of evidence-based medicine. Plastic surgery and cosmetology 2013; 1: 1-192. [Европейское руководство по лечению акне, основанное на принципах доказательной медицины. Пластическая хирургия и косметология 2013; 1: 1-192.]
  4. Belicova Yu.A., Petrunin D.D. About local administration of antibacterial drugs for acne therapy. Vestn dermatol i venerol 2010; 3: 75-85. [Белькова Ю.А., Петрунин Д.Д. О местном применении антибактериальных препаратов в терапии акне. Вестн дерматол и венерол 2010; 3: 75-85.]
  5. Stainforth J., MacDonald-HulJl S., Papworth-Smith J.W., Eady E.A., Cunliffe W.J., Norris J.F.B., Simpson N.B., Cork M.J. A singleblind comparison of topical erythromycin/zinc lotion and oral minocycline in the treatment of acne vulgaris. J Dermatol Treatment 1993.
  6. Khlebnicova A.N., Petrunin D.D. The biologic role of zinc and it is use in practical dermatology.Vestnikdermatologii I venerologii 2014; 6: 100-116. [Хлебникова А.Н., Петрунин Д.Д. Цинк, его биологическая роль и применение в дерматологии. Вестн дерматол и венерол 2013; 6: 100-116.]
  7. Bojar R., Eady E., Jones C. etal. Inhibition of erythromycin-resistant propionibacteria on the skin of acne patients by topical erythromycin with and without zinc. Br J Dermatol 1994; 130: 329-36.
  8. Dreno B., Foulc P., Reynaud A. et al. Effect of zinc gluconate on propionibacterium acnes resistance to erythromycin in patients with inflammatory acne: in vitro and in vivo study. Eur J Dermatol 2005; 15 (3): 152-5.
  9. Ross J.I., Snelling A.M., Carnegie E., Coates P., Cunliffe W.J., Bettoli V. et al. Antibiotic-resistant acne: lessons from Europe. Br J Dermatol 2003; 148: 467-78.
  10. Sugimoto Y, Lopez-Solache I, Labrie F, et al. Cations inhibit specifically type I 5a-reductase found in human skin. J Invest Dermatol 1995; 104: 775-8.
  11. Kazimierczak W, Maslinski C. The mechanism of the inhibitory action of zinc on histamine release from mast cells by compound 48/80. Agents Actions 1974; 3/4: 203-4.
  12. Lansdown AB, Mirastschijski U, Stubbs N, et al. Zinc in wound healing: theoretical, experimental, and clinical aspects. WoundRepairRegen 2007; 15(1): 2-16.
  13. Instruction on medical application of a preparation of Zenerit. [Инструкция по медицинскому применению препарата Зинерит П № 013569/01-110309.]
  14. Monahov S.A. Zenerit lotion in the treatment of acne. Pharmateca. 2007; 10: 52-57. [Монахов С.А. Лосьон зинерит в терапии акне, ФАРМАТЕКА 2007; 10: 52-57.]
  15. Albanova V.I., Sazykina L.N, Golchenko V.A. The results of postmarketing studies on the efficacy of therapy of vulgar and late-onset acne with the use of erythtromycin/zinc acetate for topical application and the influence of this disease and its treatment on the psychological status of the patient. dinical Dermatology and Venerology 2012; 3: 83-91. [Альбанова В.И., Сазыкина Л.Н., Гольченко В.А. Результаты пострегистрационого изучения эффективности терапии топическим эритромицин-цинка ацетатом при обычных и поздних угрях, влияние данного заболевания и лечения на психологический статус пациентов. Клин дерматол и венерол 2012; 3: 83-91.]
  16. Terpstra I.J. Acne treatment with 4 percent-erythromycinand1.2 per cent zinc acetate Gist-brocades Farma BV. Rijswijk. The Netherlands Proceedings of the Symposium on Acne and Related Disorders, Cardiff, March 21-23. 1988.
  17. Korchevaya T.A. Plastic surgery and cosmetology; 2012: 4 639-644. [Корчевая Т.А. Опыт использования косметических процедур в терапии акне. Пластич хирур и косметол 2012; 4: 639-644.]

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