Recurrent balanoposthitis of mixed etiology: relation to oral sex and selection of an efficient treatment method

Cover Page

Abstract


Goal. To study the dependence between the recurrent balanoposthitis of mixed etiology and oral sex. To assess the efficacy, tolerance and cosmetic acceptability of a combination topical drug on the basis of a cream for the treatment of balanoposthitis of Candida and bacterial etiology. Materials and methods. An open-label single-arm non-randomized study involved 48 men aged 22-43 suffering from recurrent balanoposthitis of mixed etiology and their long-term sex partners. All of the subjects underwent the following tests: complete blood count, clinical urine test, blood biochemistry (AST, ALT, total bilirubin, thymol test and blood glucose), MRSA, blood tests for anti-hepatitis B and C virus antibodies, HIV-1/-2 antibody screening test, microscopy of urethral, vaginal and cervical canal materials, PCR for Chlamydia trachomatis, Trichomonas vaginalis, N. gonorrhoeae, Mycoplasma genitalium, Ureaplasma spp, bacterial swab tests based on urethral materials (in men), vaginal materials (in women) and throat (in subjects of both sexes), and microscopy of tongue scrapings. 46 male patients used the Candiderm cream (Glenmark Pharmaceuticals Ltd.) for 10-14 days. Physicians assessed the efficacy based on the symptom intensity and patient’s opinion. Results. In people who practiced unprotected oral sex, a high contamination of mucous coats in the oral cavity, throat and genitals with yeast fungi and opportunistic bacteria was revealed. C. Аlbicans was often found in diagnostically significant amounts in couples. The authors substantiate the possibility of a contact-type transmission of opportunistic bacteria during oral sex resulting in balanoposthitis of mixed Candida and bacterial etiology or exacerbation of their condition after sexual contacts in men practicing unprotected oral sex. Evident clinical efficacy and safety of the combination as well as good tolerance and convenience of application of the combination topical drug comprising beclomethasone dipropionate, gentamicin and clotrimazole for the treatment of balanoposthitis of Candida and bacterial etiology.

O. B. Demianova

MEDHELP clinic

Author for correspondence.
Email: Demjanova_Olga@mail.ru

Russian Federation

A. G. Buravkova

Voronezh State Medical Academy named after N.N. Burdenko

Email: noemail@neicon.ru

Russian Federation

  1. E. Rylander, A.-L. Berglund, C. Krassny, B. Petrini. Vulvovaginal Candida in a yong sexually active population: prevalence and association with oro-genital sex and frequent pain at intercourse. Division of Obstetrics and Gynaecology, Karolinska Institutet Danderyd Hospital, SE - 18288Stockholm, Sweden. Sex Transm Infect 2004; 80: 54-57.
  2. KuznetsovaYu. K., SirmaisN. S. Treatment of skin mixed infec-tions. Vestn Dermatol Venerol 2013; 5: 132-137. [Кузнецова Ю.К. Сир-майс Н.С. Лечение микст-инфекций кожи. Вестн дерматол венерол 2013: (5): 132-137.]
  3. Rakhmatulina M.R. Modernapproachestothe therapy of vulvovaginitis caused by opportunistic microorganism staking into account the antibacterial resistance o finfectious agents. Vestn Dermatol Venerol 2013; 2: 44-52. [Рахматулина М.Р. Современные подходы к терапии вульвовагинитов, вызванных условно-патогенными микроорганизмами, с учетом антибактериальной резистентности инфекционных агентов. Вестн дерматол венерол 2013; (2): 44-52.] Литература
  4. Matushevskaya E.V., Masyukova S.A., Skripki-na P.A., Chist-yakova T.V. The combined topic corticosteroid preparations in the treatment of atopic dermatitis. Sovr probl dermatol immunol vrach kosmetol 2009; 2: 14. [Матушевская Е.В. Масюкова С.А., Скрипкина П.А., Чистякова Т.В. Топические комбинированные кортикостероидные препараты в лечении атопического дерматита. Совр пробл дерматол венерол врач косметол 2009; (2): 14.]
  5. Ryumin D.V. Diseases of the penis: manual for the doctors. The 2nd edition processed. Moskva: Rossiyskaya Medicinskaya Akademiua Posle-diplomnogo obrazovaniya; 2011: 40-46. [Рюмин Д.В. Болезни полового члена: руководство для врачей. 2-е изд., перераб. Москва: Российская медицинская академия последипломного образования; 2011: 40-46.]
  6. TikhomirovA. L., OleynikCh. G., Vaginal infections: point of view of the gynecologist. Rational therapy of Candida andmixed vulvovagini-tis. Consilium medicum. 2005; 7 (3): 40-42. [Тихомиров А.Л. Олейник Ч.Г. Инфекции влагалища: взгляд гинеколога. Рациональная терапия кандидозного и смешанных вульвовагинитов. Consilium medicum. 2005; 7 (3): 40-42.]
  7. Geiger A.M., Foxman B. Risk factors for vulvovaginal candidi-asis: acase - control study among university students. Epidemiology 1996; 7: 182-7.
  8. Maricos A.R., Wade A.A.H., Walzam M. Oral sex and recurrent vulvo-vaginal candidiasis.Genitourin Med 1992; 68: 61-2.
  9. Oates JK. Recurrent vaginitis and oral sex. Lancet 1979; 1:785.
  10. Reed B.D., Gorenflo D.W., Gillespie B.W. et al. Sexual bihaviour and other risk factors for Candida vulvovaginitis. J Womens Health Cend Based Med 2000; 9: 645.
  11. Horowitz B., Edelstein S.W., Lippman L. Sexual transmittion of Candida. ObstetGynecol 1987; 69: 883-6.
  12. Fovler J.F. et al. Hydrocortisone butirate 0,1% cream in the treatment of chronic dermatitis. Therapeutics for the clinician. Cutis 2005; (75): 125-131.

Views

Abstract - 72

PDF (Russian) - 76

Refbacks

  • There are currently no refbacks.

Copyright (c)



This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies