Androgenic hormone profile in patients with androgenetic alopecia

Cover Page

Abstract


In this article, the outcomes of the range of researches are described including the data on levels of testosterone, dihydrotestosterone, dehydroepiandrosterone sulfate, sex hormone-binding globulin and other components of androgen hormone profile in issues and biological fluids of males with androgenetic alopecia. Besides, in this article we describe results of recent studies devoted to effects of androgens on hair follicles and the role of 5-alpha reductase in conversion of androgens.

I. N. Konrakhina

State Research Center of Dermatovenereology and Cosmetology, Ministry of Healthcare of the Russian Federation

Author for correspondence.
Email: noemail@neicon.ru

Russian Federation

A. N. Mareeva

State Research Center of Dermatovenereology and Cosmetology, Ministry of Healthcare of the Russian Federation

Email: Nastasya_66@mail.ru

Russian Federation

P. A. Kalinina

Russian Medical Academy of Postgraduate Studies, Ministry of Health of the Russian Federation

Email: noemail@neicon.ru

Russian Federation

M. G. Abuladze

State Research Center of Dermatovenereology and Cosmetology, Ministry of Healthcare of the Russian Federation

Email: noemail@neicon.ru

Russian Federation

  1. Hamilton J.B. Male Hormone Stimulation is a Prerequisite and Incitant in Common Baldness. J Invest Dermatol 1942; 5 (6): 473-474.
  2. Rathnayake D., Sinclair R. Male androgenetic alopecia. Expert Opin Pharmacother 2010; 11 (8): 1295-304.
  3. Urysiak-Czubatka I., Kmiec M.L., Broniarczyk-Dy+a G. Assessment of the usefulness of dihydrotestosterone in the diagnostics of patients with androgenetic alopecia. Postepy dermatologii i Alergol 2014; 31 (4): 207-15.
  4. Trueb R.M., Lee W.S. Male Alopecia: Guide to Successful Management. Springer International Publishing AG, 2014.
  5. Райцева С.С. Клиническая эффективность применения препаратов NCTF 135/135HA и Эмбриобласт в профилактике и лечении андрогенной алопеции. 2013.
  6. Sinclair R.D. Male androgenetic alopecia (Part II) J Men’s Heal Gend 2005; 2 (1): 38-44.
  7. Pan H.J. et al. Evaluation of RU58841 as an anti-androgen in prostate PC3 cells and a topical anti-alopecia agent in the bald scalp of stumptailed macaques. Endocrine 1998; 9 (1): 39-43.
  8. Schmidt J.B., Lindmaier A., Spona J. Hormonal Parameters in Androgenetic Hair Loss in the Male. Dermatology 1991; 182 (4): 214-217.
  9. Cipriani R. et al. Sex hormone-binding globulin and saliva testosterone levels in men with androgenetic alopecia. Br J Dermatol 1983; 109 (3): 249-252.
  10. Schweikert H.U., Wilson J.D. Regulation of human hair growth by steroid hormones. I. Tester-one metabolism in isolated hairs. J Clin Endocrinol Metab 1974; 38 (5): 811-9.
  11. Yip L., Rufaut N., Sinclair R. Role of genetics and sex steroid hormones in male androgenetic alopecia and female pattern hair loss: an update of what we now know. Australas J Dermatol 2011; 52 (2): 81-8.
  12. Sreekumar G.P. et al. Serum androgens and genetic linkage analysis in early onset androgenetic alopecia. J Invest Dermatol 1999; 113 (2): 277-9.
  13. Knussmann R., Christiansen K., Kannmacher J. Relations between sex hormone level and characters of hair and skin in healthy young men. Am J Phys Anthropol 1992; 88 (1): 59-67.
  14. Narad S. et al. Hormonal profile in Indian men with premature androgenetic alopecia. Int J Trichology 2013; 5 (2): 69-72.
  15. Starka L., Hill M., Polacek V. Hormonal profile in men with premature androgenic alopecia. Sbornik lékarsky 2000; 101 (1): 17-22.
  16. Sawaya M.E., Price V.H. Different levels of 5alpha-reductase type I and II, aromatase, and androgen receptor in hair follicles of women and men with androgenetic alopecia. J Invest Dermatol 1997; 109 (3): 296-300.
  17. Camacho F.M., Garcia-Hernandez M.J., Fernandez- Crehuet J.L. Value of hormonal levels in patients with male androgenetic alopecia treated with finasteride: better response in patients under 26 years old. Br J Dermatol 2008; 158 (5): 1121-4.

Views

Abstract - 61

PDF (Russian) - 47

Refbacks

  • There are currently no refbacks.

Copyright (c)



This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies