Long-term therapy of severe acne: selection of doses and administration schemes for systemic isotretinoin

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Abstract


The article presents current data on the application of a systemic retinoid, isotretinoin, on the basis of the Lidose system for the treatment of patients with severe forms of acne. It also discusses issues of optimization of the daily dose of isotretinoin taking into consideration long-term clinical efficacy and safety of the therapy. The article presents the results of the authors’ study demonstrating the possibility to select mainly large or small doses of systemic isotretinoin depending on the treatment duration.

A. L. Bakulev

Saratov State Medical University named after V.I. Razumovsky Bolshaya

Author for correspondence.
Email: al_ba05@mail.ru

Russian Federation

S. S. Kravchenya

Saratov State Medical University named after V.I. Razumovsky Bolshaya

Email: noemail@neicon.ru

Russian Federation

A. N. Platonova

Saratov State Medical University named after V.I. Razumovsky Bolshaya

Email: noemail@neicon.ru

Russian Federation

I. A. Igonina

Saratov State Medical University named after V.I. Razumovsky Bolshaya

Email: noemail@neicon.ru

Russian Federation

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