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Нейросифилис на фоне ВИЧ-инфекции

https://doi.org/10.25208/0042-4609-2015-0-2-49-57

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Аннотация

Обзорная статья посвящена особенностям диагностики и лечения нейросифилиса, развивающегося на фоне ВИЧ-инфекции. ВИЧ-инфицированные больные сифилисом подвержены более высокому риску возникновения специфических поражений нервной системы, органов зрения и слуха, у них выше вероятность неудач в лечении сифилиса и возникновения нейрорецидивов. Диагностика нейросифилиса у ВИЧ-позитивных больных затруднена, поскольку обе инфекции вызывают сходные изменения в цереброспинальной жидкости. Эффективность терапии нейросифилиса на фоне коинфекции трудно оценить, так как нормализация состава ликвора у ВИЧ-позитивных пациентов происходит медленнее, чем у ВИЧ-негативных. Прогнозируемое в ближайшие годы увеличение частоты встречаемости сочетанных заражений сифилисом и ВИЧ диктует необходимость всестороннего изучения данной проблемы и совершенствования подходов к диагностике и лечению нейросифилиса при коинфекции.

Об авторах

Т. В. Красносельских
ГБОУ ВПО ПСПбГМУ им. акад. И.П. Павлова Минздрава России
Россия


Е. В. Соколовский
ГБОУ ВПО ПСПбГМУ им. акад. И.П. Павлова Минздрава России
Россия


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Для цитирования:


Красносельских Т.В., Соколовский Е.В. Нейросифилис на фоне ВИЧ-инфекции. Вестник дерматологии и венерологии. 2015;(2):49-57. https://doi.org/10.25208/0042-4609-2015-0-2-49-57

For citation:


Krasnoselskikh T.V., Sokolovskiy E.V. Neurosyphilis in HIV-infected patients. Vestnik dermatologii i venerologii. 2015;(2):49-57. (In Russ.) https://doi.org/10.25208/0042-4609-2015-0-2-49-57

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