T* reatment of vulgar and plantar warts

Cover Page

Abstract


The article presents data on clinical forms of warts associated with different types of human papillomavirus. The authors analyze the following wart treatment methods: excision, chemical and immune. Based on literature sources, the authors assess the efficacy, advantages and disadvantages of well-known treatment methods. The authors describe their own experience of treating primary and recurrent vulgar and plantar warts with an up-to-date chemical destruction drug - Mardil Zinc Max, a solution containing a complex compound of 1.5% zinc 2-chloropropionate in 2-chloropropionic acid. The efficacy of treatment of vulgar warts was 100%, and that of plantar ones - 62.5%. Clinical recovery was observed both in case of primary and recurrent processes. The treatment had no adverse effects or complications and was characterized by a low injury rate, good tolerance and full tissue recovery without any cosmetic defects.

A. N. Khlebnikova

I.M. Sechenov First Moscow State Medical University

Author for correspondence.
Email: alb9696@yandex.ru

Russian Federation

Ye. V. Seleznyova

I.M. Sechenov First Moscow State Medical University

Email: alb9696@yandex.ru

Russian Federation

O. V. Dorokhina

Mytishchi Regional Dermatovenerology Dispensary

Email: alb9696@yandex.ru

Russian Federation

  1. Manykin А.А. Papillomavirusa. Medical virology under editions Lvova D.K. 2008. С. 269-276.
  2. Bellew S.G., Quartarolo N., Janniger C.K. Childhood warts: an update. Cutis 2004; 73 (6): 379-84.
  3. Jablonska S., Majewski S., Obalek S., Orth G. Cutaneous warts. Clin. Dermatol 1997; 15 (3): 309-19.
  4. Plunkett A., Merlin K., Gill D., Zuo Y., Jolley D., Marks R. The frequency of common nonmalignant skin conditions in adults in central Victoria, Australia. Int. J. Dermatol 1999; 38 (12): 901-8.
  5. Silverberg N.B. Human papillomavirus infections in children. Curr. Opin. Pediatr 2004; 16 (4): 402-9.
  6. Delius H., Saegling B., Bergmann K., Shamanin V., de Villiers E.M. The genomes of three of four novel HPV types, defined by differences of their L1 genes, show high conservation of the E7 gene and the URR. Virology 1998; 240 (2): 359-65.
  7. de Villiers E.M., Fauquet C., Broker T.R., Bernard H.U., zur Hausen H. Classification of papillomaviruses. Virology. 2004; 324 (1): 17-27.
  8. Holland T.T., Weber C.B., James W.D. Tender periungual nodules. Myrmecia (deep palmoplantar warts). Arch. Dermatol 1992; 128 (1): 105-8.
  9. Cohen P.R., Hebert A.A., Adler-Storthz K. Focal epithelial hyperplasia. Heck disease. Pediatr Dermatol 1993; 10 (3): 245-51.
  10. Molochkov A.V., Khlebnikova A.N., Kuncevich ZH.S. Epithelial tumors of a skin. M: Binom, 2012.
  11. Molochkov A.V., Bagramova G.E., Gureeva M.A., Khlebnikova A.N., Kucherov V.A., Stovbun S.V., Safronov D.Yu. Immunotropic and antiviral therapy of cuteneous neoplasms associated with papillomavirus infection 2012; 2: 75-78.
  12. Bourke J.F., Berth-Jones J., Hutchinson P.E. Cryotherapy of common viral warts at intervals of 1, 2 and 3 weeks. Br. J. Dermatol 1995; 132 (2): 433-6.
  13. Glister H.M. Jr., Roenigk R.K. Risk of acquiring human papillomavirus from the plume produced by the carbon dioxide laser in the treatment of warts. J. Am. Acad. Dermatol 1995; 32 (3): 436-41.
  14. Hughes P.S., Hughes A.P. Absence of human papillomavirus DNA in the plume of erbium: YAG laser-treated warts. J. Am. Acad. Dermatol 1998; 38 (3): 426 -8.
  15. Sloan K., Haberman H., Lynde C.W. Carbon dioxide laser-treatment of resistant verrucae vulgaris: retrospective analysis. J. Cutan. Med. Surg 1998; 2 (3): 142 -5.
  16. Kwok C.S., Holland R., Gibbs S. Efficacy of topical treatments for cutaneous warts: a metaanalysis and pooled analysis of randomized controlled trials. Br. J. Dermatol 2011; 165 (2): 233-46
  17. Cockayne S., Hewitt C., Hicks K., Jayakody S., Kang’ombe A.R., Stamuli E., et al.; EVerT Team. Cryotherapy versus salicylic acid for the treatment of plantar warts (verrucae): a randomised controlled trial. Br. Med. J 2011; 342: d3271.
  18. Gibbs S., Harvey I., Sterling J., Stark R. Local treatments for cutaneous warts: systematic review. Br. Med. J 2002; 325 (7362): 461.
  19. Gladsjo J.A., Alio Saenz A.B., Bergman J., Krikorian G., Cunningham B.B. 5% 5-fluorouracil cream for treatment of verruca vulgaris in children. Pediat. Dermatol 2009; 26: 279 -285
  20. Sterling J.C., Handfield-Jones S., Hudson P.V. Guidelines for the management of cutaneous warts. Br. J. Dermatol 2001; 144: 4-11.
  21. Lewis T.G., Nydorf E.D. Intralesional bleomycin for warts: a review. J. Drugs Dermatol 2006; 5 (6): 499-504.
  22. Allam J.P., Hagemann T., Bieber T., Novak N. Successful treatment of therapy-resistant plantar verrucae vulgares with systemic interferon-beta. J. Dermatol 2004; 31 (7): 582-3.
  23. Aksakal A.B., Ozden M.G., Atahan C., Onder M. Successful treatment of verruca plantaris with a single sublesional injection of interferon-alpha2a. Cline. Exp. Dermatol 2009; 34 (1): 16-9
  24. Bagramova G.E., Sedova T.G., Khlebnikova A.N. Russian magazine of skin and venereal diseases 2013; № 1: 23-26.

Views

Abstract - 128

PDF (Russian) - 167

Refbacks

  • There are currently no refbacks.

Copyright (c)



This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies