Vol 87, No 4 (2011)

The author presents an analysis of prevalence of atopic dermatitis among children at the age of 0-14 and teenagers at the age of 15-17 on the basis of data from official public statistical reports for the Russian Federation and for territories of Ural, Siberia and Far East for the period of 2005-2009.

The authors present a review of research publications about clinical significance of using modern immunochromatographic methods for determination of anti-immunodominant antigen antibodies of syphilis pathogen Treponema pallidum. Immunochromatographic sets of chemicals proved to be convenient in use, can be used with a small amount of biological materials, do not demand any specialized medical equipment, have high sensitivity and specificity, in particular, for tests with blood serum or plasma samples; when whole blood samples are used, this reduces the method sensitivity. Immunochromatographic tests are intended for prompt express examination of the population to reveal syphilis patients under field conditions or at medical institutions consulting primary patients and not having their own clinical laboratories.

The authors describe the use of spectrophotometry intracutaneous analysis method for the purposes of differential diagnostics of pigmented skin neoplasms.

The author describes current approaches to treatment of vulvovaginites caused by opportunistic microorganisms. The author assessed clinical and microbiological efficacy of different methods of treatment used for this pathology.

The authors describe the results of a clinical study of 90 patients suffering from different clinical forms of atopic dermatitis (AD), who received hepatotropic drugs in combination with ursodeoxycholic acid. A misbalance of cellular and humoral immunity was revealed in these patients prior to the onset of treatment. The inclusion of ursodeoxycholic acid in complex treatment of AD contributed to normalization of immunity indices and regression of skin eruptions.

The paper presents the clinical case of Pseudosarcoma Kaposi (Mali type) of patient at age of 45 years. Its manifestation was induced by trauma and this was not a congenital vascular dysplasia as in Pseudo - Kaposhi sarcoma (Stewart - Bluefarb type).

The authors describe a rare form of scarring alopecia - central centrifugal scarring alopecia (synonym: follicular degeneration syndrome). A particular feature of this disorder is a combination of scarring alopecia with pathology of the thyroid gland. The authors also provide a classification of primary scarring alopecias.

Remedial measures for photodamages of skin are mainly aimed at elimination of inflammation and subjective sensations such as burning and itching. Topical corticosteroids remain leading drugs in the external therapy of phototrauma, phototoxic and photoallergic reactions. Mometasone furoate (Elocom) has high anti-inflammatory and antiallergic activity. Moreover, the composition of the Elocom cream is based on titanium dioxide, a classical mineral screen, which makes it possible to use the Elocom cream in case of steroid-sensitive pathology under conditions of high solar exposure. The Elocom cream has been used in the monotherapy and complex treatment of solar dermatitis, actinic cheilitis, polymorphous light eruption, discoid lupus erythematosus and actinic prurigo. Regression of manifestations of solar dermatitis was recorded on Day 1-3 of treatment, and regression of manifestations of actinic cheilitis - during Week 2 of treatment. The process in case of photoallergic reactions and discoid lupus erythematosus was over during Week 3-4 of treatment. Substances making a part of the composition of the Elocom cream and having photoprotective properties make this cream a drug of choice for its use on skin areas subject to solar exposure in case of steroidsensitive pathology including phototrauma, phototoxic and photoallergic reactions. Besides, photoprotective properties of the Elocom cream explain why it should be selected for treatment of steroid-sensitive dermatoses becoming more severe or appearing after solar exposure, in case of localization of eruptions on open skin areas (face, neck, decollete area, hands, etc.)

The authors present the results of examination and treatment of 40 female patients with recurrent urogenital infections, who had optional and/or obligate anaerobes revealed by bacteriological tests (patients were withdrawn from the study if Neisseria gonorrhoeae, C. trachomatis, Treponema pallidum or Trichomonas vaginalis were revealed). The patients received treatment with doxycycline or josamycin depending on the results of determination of sensitivity of cultivated microorganisms. Evident positive dynamics of clinical manifestations was recorded as a result of use of these drugs. Normalization of biocenosis and absence of opportunistic flora were recorded for 38 patients.

The authors present the results of a study involving 80 patients suffering from inflammatory diseases of the urogenital system caused by mixed pathogenic and opportunistic urinogenital infection. The patients underwent clinical and laboratory examination; clinical characteristics of the course of the disease were recorded. The study results demonstrated clinical and microbiological efficacy of Safocid, a combined drug used for treatment of this group of patients.

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