Using clobetasol propionate in the form of a shampoo for the treatment of patients suffering from psoriasis localized in the scalp area

Cover Page

Abstract


The study involved 80 adult psoriatic patients with scalp affections at the dermatosis progressing stage. The authors compared scalp psoriasis topical treatment options such as using 0.05% clobetasol propionate in the form of a shampoo, and successive administration of the 2% salicylic acid ointment and aforesaid short-term topical product in patients with vulgar or exudative dermatoses using dynamic scores such as mPASI, DLQI and itching intensity degree. It was demonstrated that 0.05% clobetasol propionate used in the form of a shampoo is characterized by a high efficacy and safety profile for patients with vulgar or exudative psoriasis of the scalp. At the same time, in case of exudative dermatosis successive topical treatment with the use of the 2% salicylic acid ointment and 0.05% clobetasol propionate in the form of a shampoo contributes to the clearance of psoriatic foci from accumulated scales and enables a potent topical corticosteroid such as clobetasol to efficiently reduce principal clinical symptoms of scalp psoriasis such as erythema, infiltration, exfoliation and itching. Using the clobetasol shampoo reduces the scalp itching intensity as the key psoriatic symptom preventing an isomorphic reaction as a result of foci traumatization related to scratching.

About the authors

A. L. Bakulev

Saratov State Medical University named after V.I. Razumovsky

Author for correspondence.
Email: al_ba05@mail.ru

Russian Federation

S. S. Kravchenya

Saratov State Medical University named after V.I. Razumovsky

Email: noemail@neicon.ru

Russian Federation

I. A. Igonina

Saratov State Medical University named after V.I. Razumovsky

Email: noemail@neicon.ru

Russian Federation

S. R. Utz

Saratov State Medical University named after V.I. Razumovsky

Email: s_utz@mail.ru

Russian Federation

References

  1. Szepietowski J.C., Reich A. Pruritus in psoriasis: An update. EJP. 2015; 20: 40-46.
  2. Gelfand J.M., Feldman S.R., Stern R.S., Thomas J., Rolstad T., Margolis D.J. Determinants of quality of life in patients with psoriasis: a study from the US population. J Am Acad Dermatol 2004 Nov; 51 (5): 704-8.
  3. Blakely K., Gooderham M. Management of scalp psoriasis: current perspectives. Psoriasis: targets and therapy 2006: 6; 33-40.
  4. Stein Gold L.F. Therapies for psoriasis: improving management. Strategies and patient adherence. Seminars in cutaneous medicine and surgery 2016; 35 (2S): 36-46.
  5. Gelfand J.M., Feldman S.R., Stern R.S., Thomas J., Rolstad T., Margolis D.J. Determinants of quality of life in patients with psoriasis: a study from the US population. J Am Acad Dermatol 2004 Nov; 51 (5): 704-8.
  6. Villani A.P., Rouzand M., Sevrain M., Barnetche T. et al. Symptoms dermatolosistss-hould look for in daily practice to improve detection of psoriatic arthritis in psoriasis patients: an expert group consensus. JEADV 2014; Supp. 5: 27-32.
  7. Ortonne J, Chimenti S, Luger T, Puig L, Reid F, Trüeb R. Scalp psoriasis: European consensus on grading and treatment algorithm. J Eur Acad Dermatol Venereol 2009; 23: 1435-44.
  8. Jarrat M, Breneman D, Gottlieb AB, Poulin Y, Liu Y, Foley V. Clobetasol propionate shampoo 0.05%: a new option to treat patients with moderate to severe scalp psoriasis. J Drugs Dermatol 2004; 3: 367-73.
  9. Poulin Y., Papp K., Bissonnette R. et al. Clobetasol propionate shampoo 0.05% is efficacious and safe for long-term control of scalp psoriasis. Cutis 2010; 85: 43-50.
  10. Jheta A., Fawcett J.M., Berker D Topical treatments for scalp psoriasis: evidence - based guide 2016; Jan: 38-41.

Statistics

Views

Abstract - 1099

PDF (Russian) - 443

PlumX

Dimensions


Copyright (c)



This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies